ALCAR The Ultimate Guide
What is ALCAR (Acetyl L-Carnitine)
You may have seen carnitine on your health food shop shelves and wondered about exactly what it does and how it might of benefit to the human body. The following should tell you everything you need to know about this important substance and why it might be worth investing in.
Carnitine is sometimes referred to as L-carnitine or Acetyl-L-carnitine (ALCAR) and is an amino acid – one of twenty which the human body produces. Each amino acid has special properties and in the case of carnitine, it is the metabolizing of fat. Carnitine helps the body to transport fat through the body so that it can be converted into energy. It will also help in the absorption of certain nutrients, especially calcium.
Although research into whether carnitine is helpful as an aid to weight loss have failed to show a link, it is possible that this is due to short research periods. Some studies have indicated that it could increase muscle mass and reduce fatigue which could lead to weight loss for those who exercise.
As well as these important functions carnitine is thought to help people afflicted with diabetes, liver disease, and even Alzheimers. It is also thought to be a powerful antioxidant and could help in problems to do with bone loss.
The word carnitine comes from the Latin for flesh (carnus) and in its isolated form, it comes from meat. Obviously, this means that we can find sources of carnitine in protein-rich foods such as meat, fish, dairy, whey and some vegetables.
A diet which consists of red meat eaten daily will provide around 60 to 180 milligrams of carnitine each day. This is then sent to the kidneys where it is held until required. If more than is required is consumed it is excreted via the kidneys in the urine. For most people, this level of carnitine is more than enough as the kidneys store the amino acid until it is required.
Carnitine deficiencies can occur as a primary condition which often shows itself in children around five years of age. These children suffer from low muscle tone and weakness. A secondary deficiency may occur due to kidney problems, renal failure or due to the use of medicines such as antibiotics. For this reason, supplementing with carnitine can be useful for some people.
In recent years carnitine has been used as a supplement for people who want to achieve certain health benefits. Athletes take carnitine because it is believed to improve performance, although the research does not back this up. It is also thought that carnitine may slow the aging process as it might reduce mitochondrial decay. Other studies have indicated that it might be useful in the treatment of cardiovascular disease, HIV, type II diabetes, male infertility and even cancer.
While there may be health benefits of taking supplemental carnitine, there are some associated reactions from high doses. At around 3 grams per day, users may experience vomiting, nausea, cramps and loose stools. Rarely it can cause muscle weakness and seizures in people who are prone to them.
Carnitine vs L-Carnitine vs Acetyl L- Carnitine (ALCAR) : What’s the Difference?
Carnitine is an amino acid which is one of the building blocks of protein in the body. It is a naturally occurring substance which is found in most protein foods and can be easily assimilated by the human body. Most people make enough carnitine for the immediate bodily functions from the food they eat, although it is possible to supplement it for extra benefits.
The benefits of carnitine include extra energy, increased body fat metabolism, and increased muscle building. Other benefits include improving mental function and some relief from certain conditions such as memory loss and fatigue.
For the above reasons, carnitine is a popular supplement, especially in the bodybuilding world where it is thought to give extra energy for longer and more effective workouts. However, many people are very confused about the different names which appear to be associated with carnitine and the different ways in which it is sold.
Carnitine and L-carnitine are essentially the same things. The “L” in front of any amino acid simply represents the fact that it is one of the amino acids which can be separated into two types. These are usually “L” and “D”. The “D” form is only ever made by scientists and is not readily used by the body. However, the “L” form is used by the body. Whenever the word carnitine is used it almost always refers to L-carnitine.
The difference between L-carnitine and acetyl l-carnitine is a little more complicated. When using a supplemental form of l-carnitine the body finds that it cannot be absorbed as readily as the acetyl l-carnitine which is in a form which enters the bloodstream more quickly.
Acetyl l-carnitine (ALCAR) is thought to reach the brain more quickly and will, therefore, affect mental energy levels to a higher degree. In addition, it also offers greater mental clarity and often a euphoria like state
When it comes to the structural difference between the two substances, the acetyl l-carnitine is a molecule which comes from the l-carnitine which contains an acetic acid grouping. This is a small difference structurally but changes the way it works quite radically. L-carnitine is the parent form of acetyl l-carnitine.
Acetyl l-carnitine has neuroprotective properties and will help in the process which allows carbohydrates to be used for energy. It can also protect the nervous system, something which l-carnitine does not do. It also protects the mitochondria which are the cells which transport energy around the body.
For those who wish to gain the best benefit from taking a carnitine-based supplement, it does seem that the acetyl based product is the best option. It can be found in protein-based food, but vegetarians and particularly vegans may find that taking a supplement is wise. Especially if they enjoy bodybuilding or other sports. It is also thought that the body produces less of this amino acid as we age, so supplementing may be a good idea in later life.
L-Carnitine and CLA (Conjugated Linoleic Acid)
Many people who are interested in losing weight and building muscle are turning to two supplements in combination to help them achieve their goals. L-carnitine and CLA are regarded by experts as being two of the more potent fat loss and muscle building aids and often sold in combination. But how effective are they likely to be?
L-carnitine is an amino acid which also known as the body’s protein building blocks. It is naturally available in most protein-based foods and is stored in the body until required. It is known to help the body to get energy from food via the mitochondria. In addition to improving energy levels, it is also thought to improve mental and cognitive function.
For these reasons, L-carnitine is often used in the bodybuilding world to allow athletes to perform for longer and at a higher intensity. It is also used by people who are suffering from memory impairment. As the body appears to have problems making L-carnitine as it ages, supplementation by those aged of 50 is sometimes recommended.
Conjugated Linoleic Acid (CLA) is a fatty acid which is also found in animal products, in particular, beef and dairy. It was first discovered when scientists used a beef extract on mice which had been exposed to a cancer-causing substance. The mice went on to develop 20% fewer tumors than those not using the substance. For this reason, CLA is thought to be effective as an anti-cancer supplement.
Other studies have shown CLA to be effective in weight management, especially how it reduces body fat and improves muscle mass. It is considered to be a safe supplement and is included in a number of everyday foods.
A number of studies have indicated that a dosage of 3 grams a day of CLA can result in a loss of 90 g of fat each week, while higher doses didn’t seem to offer any additional benefit. In addition, it could add another 1% increase in lean body weight each week. It is regarded as a good tool in the fight against excess weight when used as part of an overall package of exercise and diet.
Despite this good new CLA is not advised for those people who are at risk of developing type II diabetes as it can increase insulin resistance. For this reason, it is not advised for people who are already very overweight.
These two supplements will work well together. The L-carnitine will give the user more energy to perform the extra exercise as well as more focus and mental clarity. It is also possible that the exercise will be carried out to a more impressive degree, accelerating the results. Meanwhile, CLA will help to melt away fat during exercise and will improve the way the body builds muscle.
These two supplements are sold individually but are also available as a combination. It is important to ensure that the correct dosage is being taken for your individual needs and requirements.
N-Acetyl Carnitine not just for Bodybuilding and Athletes
N-acetyl carnitine is a form of L-carnitine which is more readily available for the human body to make use of. For this reason, it is more easily absorbed into the body and can be used more effectively in the mitochondria of cells. This assists in improving energy levels and could possibly improve concentration and cognitive function. It is also thought to improve how fatty acids are used for energy.
As one of the twenty amino acids produced by the body, N-acetyl carnitine has an important role to play in the production of protein and therefore muscle. It is sometimes referred to as L-carnitine or acetyl l-carnitine, but the body can actually produce one of these substances from the other and vice versa, depending on its requirements.
However, there is no clear evidence whether the benefits derived from the amino acid come from which form. However, it does seem that ingesting N-acetyl carnitine makes it easier for the body to use it.
One study has suggested that L-carnitine on its own only enters the bloodstream if accompanied by a carbohydrate spike. However, the acetyl version seems to be absorbed more easily.
This supplement is thought to be useful for a number of reasons. These include:
- Memory issues such as Alzheimer’s
- The recovery of stroke patients in terms of their thinking skills
- The nerve pain caused by diabetes
- Male infertility
- Testosterone deficiencies
- Improved blood flow to the brain
There is also some evidence to suggest that N-acetyl carnitine might be useful for:
- Downs syndrome
- Lymes disease
- Nerve problems
- The symptoms related to taking HIV medication
- For people suffering from chronic fatigue syndrome
N-acetyl carnitine is most often sold as a supplement for bodybuilders who wish to burn more fat as fuel and build muscle. It is claimed by those who sell it for this purpose that the amino acid could assist in endurance as well as improve how body fat is used for energy. In addition, it could improve cognitive function, which is useful for people who workout on a regular basis.
The cognitive function benefits of N-acetyl carnitine will allow a bodybuilder or athlete to remain focused and full of energy when they are performing.
It is recommended that anyone wanting to take this product as a supplement should take around 3mg once or twice daily. It comes in a liquid form and simply be stirred into a drink – orange juice is recommended.
Unfortunately, there is little evidence or research to show that N-acetyl carnitine is actually useful for athletes, but it has been shown to be relatively harmless if taken in the correct dosage. Some of the minor side effects might be nausea, vomiting, stomach cramps and a strange body odor. The more of the supplement which is taken, the higher the chance of side effects.
If you are taking any other medications it is important to speak to your doctor before supplementing with N-acetyl carnitine as it can cause interactions.
Carnitine Side Effects and Limitations
Carnitine which is sometimes called L-carnitine or acetyl-L-carnitine (ALCAR) is used by the body to improve the metabolism of fat and the production of muscle. It is also an antioxidant which may possibly improve or slow down the aging process. It is also used in the treatment of heart and cardiovascular problems. For these reasons and host of others, carnitine is a very popular supplement or prescription drug.
For most people the amount of carnitine which is found in protein-based foods such as meat, dairy products and some vegetables and grains is plenty. But there are also many products available which contain varying amounts of carnitine. For most people around 500 to 1000 milligrams, three times a day is recommended.
However, as with most supplements, the human body already produces enough carnitine in almost all cases. Some people may be born with conditions which limit their ability to produce carnitine and for them supplementation is essential. For others, higher than required doses may be taken to take advantage of the perceived health benefits. It is also thought that the body produces less carnitine as we get older, making supplementation even more attractive.
Of course, in high does, carnitine can cause some side effects. It is important to keep these in mind if you are considering using carnitine as a supplement. It is considered to be safe when taken as a supplement or as an injection but could cause the following minor and major side effects.
- Nausea and vomiting
- Stomach upsets
- A stuffy nose and headache
- Seizures for those people who are prone to seizure disorders. Anyone who has had a seizure in the past should avoid using carnitine.
- Some people have reported restlessness and problems sleeping so it best to take carnitine earlier in the day.
- Changes to blood pressure and a fast heartbeat.
- High energy levels
For most people, these side effects are relatively minor although the more serious effects must be checked out by a doctor.
Carnitine is not recommended for pregnant or breastfeeding women but can be used in the short term for children if prescribed by a doctor. However, people with an under-active thyroid should avoid the use of carnitine as it is known to make hypothyroidism worse.
Some medicine does not react well with carnitine including medicines prescribed for blood clotting disorders. It is thought that carnitine might increase the effectiveness of these medications making blood clot too quickly. In fact, anyone who is taking medication for any condition should consult a doctor before using carnitine as a supplement.
However, not all side effects of carnitine are negative. The following list are some of the benefits which are thought to be associated with taking the amino acid.
- Fat loss
- Increased muscle mass
- Increased bone mass
- Reduce the need for angina medication
- Improve kidney function
- Male infertility
- Improved type II diabetes
- Improved immunity
- Improved brain function
As one of the twenty amino acids produced by the body, carnitine has an important job as the metabolizer of fat for the human body. Amino acids are considered to be the building blocks of protein and without them, we would be unable to use protein for energy and for muscle building.
As well as these considerable benefits, some people take carnitine as a supplement in order to treat a number of ailments and to improve their general health. It is most notably used by bodybuilders to help in the break down of fat, the conversion of protein-based foods into energy and then the building of muscle tissue.
Other benefits associated with the supplemental use of carnitine are the following:
The treatment of a deficiency of carnitine caused by genetic factors. Some people are born with conditions which prevent them from producing enough carnitine and they require regular carnitine supplements to maintain their muscle.
The treatment of kidney disease and renal failure. It works by increasing the red blood cell count.
Premature babies are thought to benefit from carnitine as it helps them absorb other nutrients.
Carnitine may improve the complications of heart disease and heart failure.
Some of the symptoms of high thyroid levels are thought to alleviate by taking carnitine.
Some studies have indicated that male infertility may be improved by the use of carnitine. A study conducted in 1979 has shown that sperm viability was improved when carnitine was introduced to the diet. The men took between 1 gram and 3 grams per day with their meals and a definite improvement in sperm quality was noted.
It is suggested that carnitine may be useful for athletes to improve performance. It is thought to improve fat loss and muscle building as well as increasing energy levels. However, there are few studies which have shown any huge benefit.
Cancer, celeriac and hepatitis C patients may have increased energy levels when taking carnitine as they may have become deficient.
There are some ADHD symptoms which may be relieved by taking carnitine.
Other conditions such as leg ulcers, type II diabetes, Lymes disease, and autism have all been said to be improved by the use of carnitine.
Chronic fatigue syndrome has also been treated with carnitine. A study showed that people with higher levels of blood carnitine were less likely to suffer from CFS. Those who were treated in the study had improved energy levels by the end of the eight-week trial.
Carnitine can be found in protein-based foods or in a supplement form from health food shops or online. While your body usually produces plenty of carnitine for everyday living, those who suffer from certain conditions or who want special benefits may wish to take extra carnitine.
It is considered safe when taken orally for short periods of time. While it is possible to find carnitine in the injectable form, it is designed for use in animals and has not be approved for humans.
Carnitine which is also known as L-carnitine and is an amino acid which is responsible for the metabolism of fat in the human body. There are twenty amino acids which the body produces and most are produced in sufficient quantities to be used effectively.
Carnitine has been used in a supplemental form by bodybuilders and those seeking certain health benefits for a number of years. Those benefits include increased body fat removal and increased muscle production. In addition, there is some evidence that carnitine can slow down the aging process due to its antioxidant properties.
Carnitine can be isolated from meat products and made into a form in which the human body can use. As it is found in most protein-based foods carnitine can be supplemented by increasing your consumption of those foods. However, some people prefer to use supplements to ensure they are getting a beneficial dosage.
Carnitine can be found in a number of forms, most often it is added to protein powders or drinks designed for athletes and bodybuilders. In other forms, it is found in capsules or as a liquid form. In the liquid form, it can be injected into fatty or muscular areas of the body. The injectable form of carnitine is actually derived from an injection which is given to horses to improve performance.
There is some debate as to how effective taking carnitine in the injectable form actually is. Some studies appear to indicate that injecting it into specific areas can actually decrease fat from that area alone. Although actual evidence of this is thin.
It is thought that the administration of carnitine can actually protect muscle tissue from damage caused by exercise as it can stimulate blood flow to the area. For this reason, it is important to get the carnitine to the muscles as efficiently as possible. Taking the supplement via the stomach can mean that the effects on the muscles are not as useful.
For some people, the use of carnitine by injection is advised by their doctor. These people may be born with a condition which stops their body from producing carnitine in the correct amounts. This means that they suffer from a chronic deficiency. It is also possible for people with blood flow issues to have carnitine prescribed.
In the UK injectable carnitine is very difficult to buy. It is available from pet supply sources or from overseas websites. These sources may be unsafe for humans and are not recommended. It has been pointed out that drugs intended for animals may not be as stringently tested as those designed for humans and as such, it may not be wise to buy them for that purpose.
Carnitine sold as a supplement in the powder form is not considered harmful and the side effects, for healthy people, are relatively minor. However, carnitine by injection is untested and as such should be used with caution.
The evidence for whether carnitine is actually useful for building muscle and fat loss is actually quite patchy. It is known to increase energy levels and may prevent muscle exhaustion and lactic acid build up, but it may not have very far-reaching results. However, it is still considered to be a worthwhile supplement for the bodybuilding industry.
Taking Carnitine with Arginine
L-carnitine and arginine are amino acids that improve the circulation, assist in burning fats, and increase energy. L-carnitine is beneficial in facilitating the transportation of fats into the mitochondria, which is an essential component for the creation of energy. It is also known to improve the functioning of the brain activity and the neurotransmission activity, fixing damages to the nerves, and enhancing the heart functioning.
Several studies provide numerous positive outcomes in patients suffering from atherosclerosis when provided with this supplement.
According to these studies, patients were able to exercise more without feeling any pain in their chests while also being able to reduce the dosage of their heart medications. Additionally, these were beneficial in improving the functionality of the body muscles even under stressful circumstances and showed an improvement in the signs of congestive cardiac failure.
Another benefit of L-carnitine is the increase in the production of acetylcholine, which affects the memory and cognitive functions. Moreover, it is known to activate muscular activities, controlling the autonomic nervous system, and is known to improve attention and arousal in a person. Another significant advantage of this amino acid is its capability to increase the rate of metabolic activity and increasing the metabolism of fatty acids. Therefore, you can reap more benefits from your workout regime because of your body capability of burning fat increases.
Arginine boosts the production of nitric oxide, which is instrumental in the circulation of the blood and facilitates continuous blood flow through the entire body. Moreover, nitric oxide is crucial in dilating the blood vessels, controlling the blood pressure levels, and providing oxygen and other important nutrients to all parts of your body. Additionally, this amino acid is vital in the division of the cells, eliminating ammonia from the body, and releasing a higher amount of hormones.
Another excellent benefit of this amino acid is its ability to vasodilate the blood vessels, which is the process by which the arteries and the blood vessels. This acts as a direct responsive system for a localized requirement of nutrients and oxygen. In other words, when a specific part of the human body requires a higher amount of oxygen and other nutrients, the blood vessels in that area vasodilate to improve the blood circulation in the region. As the circulation improves, the amount of oxygen and nutrients reaching the area increases; this entire procedure receives a boost with the use of arginine.
Cholesterol classified in two categories is a plaque like an element that builds up in the inside the walls of the various arteries. Although the human body requires cholesterol for normal functioning, an excessive amount of bad cholesterol is a leading cause of heart attacks and strokes. The excessive build-up of bad cholesterol reduces the capability of your blood vessels to produce nitric oxide affecting the blood circulation and blood pressure. However, arginine is beneficial in reducing the cholesterol levels within the body and improving the peripheral blood circulation.
A study by the Center for Disease Control and Prevention found more than thirty-one percent of Americans suffer from high blood pressure. Hypertension is a leading cause of several other illnesses, which can affect the quality of your life and maybe fatalistic. However, arginine is known to benefit the heart by increasing the efficiency of the heart beats. This helps to increase the blood flow to all parts of your body and more specifically to every chamber of your heart.
Another major benefit of this amino acid is seen in patients who suffer from arrhythmia, which is the disease that causes irregular heartbeats. When this supplement is included in the patient’s diets, they show a significant improvement in the decrease of arrhythmia.
These amino acids are also beneficial in improving the efficiency of your body’s immune system as these are known to increase the strength and the size of the thymus. The thymus produces fighting cells that prevent infections within our bodies. As you age, the flow of oxygen reaching the brain reduces, which decreases the functioning of the brain. However, including these supplements increases the flow of blood to the brain, which provides the necessary oxygen for the normal functioning of the brain.
Another major benefit of L-carnitine and arginine is its benefit to overcome the problem of erectile dysfunction. The ability of these supplements to increase the blood flow and relax the walls of the arteries enables the penis muscle to relax, which enables men to overcome this symptom and enjoy a better sexual life. Therefore, from the above discussion, it can be seen that these supplements provide numerous benefits for the smooth and normal functioning of the human body.
The Rise of Acetyl L-Carnitine with Alpha Lipoic Acid (ALA)
Although relatively unknown even a couple of decades ago, acetyl l-carnitine alpha lipoic acid are substances that have had the scientific community in something resembling euphoric hysteria.
While the level of excitement created in medical circles is, if anything, nothing short of seismic; there is an amazing level of skepticism that is spreading fast as to the effectiveness of the supplements. A considered look at what options are opened up by the drug is therefore important at this stage.
The search for the fountain of eternal youth is the stuff of legend. From archaic tales to the most gritty science fiction accounts, it seems humanity cannot end its endless fascination with the possibility that once it might be possible to live for decades with our organs still firm and supple.
The rise of acetyl l-carnitine (ALCAR) alpha lipoic acid (also referred to collectively as LA/ALC) has all the markings of moving this novel concept of make-believe to actual living fact. To understand the relative popularity of the substances, a little background is necessary.
While there had been little evidence to illustrate it, scientists have for a time suspected that humans age as they do due to the effects of free radicals in the body. These compounds mount an onslaught of attacks aimed at the body cells as well as the genetic code they are imprinted with.
Quite counter-intuitively, these radicals are as a result of the normal and essential metabolic processes that burn nutrients in the presence of oxygen to power our bodies. It is indeed difficult to imagine that a substance as crucial to our existence as oxygen could also be the source of such a destructive consequence.
The essential cell component that is involved in the generation of energy is the mitochondrion (plural mitochondria). In effect, each mitochondrion is a tiny furnace or engine that powers all cellular activity and, as a consequence, the organs and the body as a whole to continue living. The longer the mitochondria burn oxygen, the more they are subjected to free radical damage. At an advanced age, the damage wrought on the components is so extensive as to make them quite inefficient at the task. This inefficiency brings about a decrease in cellular energy supply and eventual aging.
When there was adequate proof that this was the most scientifically reasonable explanation for human aging, many scientists got hard at work. Soon a breakthrough was announced in a study conducted at the University of California. Here, scientists made some startling conclusions by observing the brain activity of young rats, old rats as well as old rats who had been injected with LA/ALC. Of the 3 groups, the one comprising older rats who had received LA/ALC treatment showed the least antioxidant activity and mitochondria deterioration. In fact, these older rats showed far more enthusiasm of bodily activity than the younger control group.
On further analysis, it was clear that the administration of LA/ALC supplement ensured that the mitochondria damage in the brains of the older rats was effectively undone. In effect. It was established that controlled intake of the two supplements can halt and even reverse cellular damage in the brain that comes with an increase in age. Furthermore, the research established that intake of nutrients targeted at brain mitochondria can significantly reduce the oxidative damage of cells and tissue.
Further research over the last couple of years has indicated that when the supplements are ingested over time and in required dosages they help with memory. It is especially significant to note that both spatial and temporal dimensions of memory are improved significantly. Even more notably, there have been studies that have proven that adding the compounds to the daily diet leads to improved activity, energy, and sharpened cognition ability.
One of the most debilitating diseases that affect people in old age is the Parkinson’s disease. Research carried out in China sought to establish if these two compounds could help combat the menace effectively. Using a human cellular model of the Parkinson’s disease these scientists were able to establish that daily intake effectively tackled the possibility of the disease arising in the individual, naturally. Though still unproven in an actual clinical trial, every indication is that a combination of LA and ALC will finally be the established method of preventing the disease.
In an age where there are endless offers of products that promise a better life with less worry and sufferings, most of which end up as spectacular flops, you can be forgiven for feeling skeptical. Going by the amount of research done in the recent past, there is every reason to believe we are at the threshold of a major breakthrough. In terms of novelty and lasting impact, the news about acetyl l-carnitine alpha lipoic acid will take some beating to be exceeded.
Diet and Genetic L-Carnitine Deficiency and Weight Loss
Lacking some form of nutrient in the body is not an uncommon occurrence. Whether it is a vitamin or chemical our system needs to function at peak performance, everyone is short on something. Understanding how to get the substances our bodies need and how they affect performance may shed light on carnitine deficiency and weight loss.
Millions of people around the world suffer from or have battled with weight issues. Maintaining a healthy weight for some can prove to be more of a challenge than mountain climbing. However, for some, it may be more than just an inconvenience. There could be underlying reasons for the inability to shed the weight.
Carnitine is a nutrient produced naturally within the body by the liver and the kidneys. It is a necessary component needed by the body to burn fatty acids which in turn is used as energy. It can also be obtained by eating certain, yet common foods. Once produced, the body stores it in certain organs, such as skeletal muscles and the heart, for later use.
Many people are deficient, but on average not enough to require anything more than adding the right foods into the diet that the body can acquire it from. Items such as red meats, dairy, chicken, and pork all contain the substance. This makes getting the supplement through food a bit tougher for vegetarians and virtually impossible for vegans.
Supplements can be purchased over the counter from drugs stores and vitamin shops, as well as online. There are various forms to choose from. The most common and the least costly form is L-carnitine. Other forms such as Acetyl-L-carnitine (ALCAR) and Propionyl-L-carnitine are more commonly used for the treatment of Alzheimer’s and heart disease.
Dosage amounts are dependent on the circumstances prompting the need for supplements. However, the usual doses for correcting a marginal shortage in this nutrient are within the 1 milligram and 3-milligram range. Higher doses, for example, 5 milligrams, may cause the onset of mild side effects such as diarrhea. Consultation with a doctor will better help determine what the correct dose is.
Signs of the more serious illness, called primary carnitine deficiency, are normally spotted in early childhood and as early as infancy. This rare disorder may be accompanied by other serious symptoms such as a weakened or enlarged heart or muscle weakness.
This disorder is inherited through genes. Both parents must also have the same syndrome for the child to be born with it. The number of children born with this in Japan is 1 out of 40,000. Unfortunately, there is no research on the ratio for the United States.
There are some individuals that only show signs in or after certain situations. Secondary carnitine deficiency is more common. This condition can be genetic or can be developed later in life. Symptoms may be triggered by fasting or after a period of illness where mineral-rich food intake was minimal. Damage to the kidneys or the liver can also cause a decrease in the production of carnitine.
Not being able to burn the fat stored around the heart can lead to many very serious health problems. Heart attack and heart failure are among the more severe. If too much fat is stored within the heart this can cause what is called plaque, to build up in the arteries.
Plaque growth on the walls of the blood vessels can cause several different health issues in itself. Hardening of the arteries is possible when there is too much build up. Tissues and muscles that do not receive oxygenated blood, can over time deteriorate and die.
Cramping in the legs while walking or exercising can be a result of blood not being able to travel through the veins. The onset of angina occurs when the muscle around the heart is not supplied with enough blood containing oxygen. Angina is a symptom of heart disease.
Another side effect of this shortage is a heart attack. When blood cannot reach the heart for prolonged periods of time, the heart muscle can become damaged or even die. Unfortunately, those who have suffered from one heart attack greatly increase their chances of having another one.
Knowing how the body works, and what it needs to do so correctly is information that everyone needs. Wanting to figure out if carnitine deficiency and weight loss are connected, or if the symptoms someone is experiencing are serious, knowledge of health matters is invaluable. Asking questions and doing research is the best way to arm yourself with the information to stay healthy.
Carnitine is nutrients that move fatty acids into mitochondria to produce energy which makes it an energy storage system within the human body. Together with this, the same nutrients are responsible for the development of important brain chemicals known as acetylcholine. A carnitine supplement dose can be taken to increase the effectiveness of the chemical production within the human body.
There are generally two forms available. One in the drug form and the other is in the form of health supplements.
The drug form has a different effect within the body as it is mostly aimed at mental benefits. The health supplements, however, show benefits of increased energy and weight loss. This is why one will notice that the drug form suggests lower doses daily whilst the other suggests very high doses more than once per day.
This is taken mostly for mental sharpness and the most common reasons for adding this to a diet is for more mental focus and stamina, sharper vision and mental motivation as well as being more alert. Some users of these pills have noticed a quick increase in physical energy, but not so much mental imagery as expected.
For people who would like to take this on a long-term basis should consider a daily dosage of between one hundred and three hundred milligrams once daily. Medical experts recommend taking a break of one to two days within a week from taking the supplement and regular users have all reviewed this recommendation as beneficial.
Studies have shown proven results from using these pills. These studies include ADHD benefits in the sense that it reduced hyperactivity much more than a commonly taken drug called placebo. Children who were tested also showed great improvement in their social behavior. This medication was also tested on people suffering from Alzheimer disease, but unfortunately, none of the people taking it showed any response to it being beneficial.
It very often occurs that people who undergo long periods of chemotherapy complain about a decrease in memory activity. There have been numerous reviews that since taking a carnitine supplement dose they experienced a positive increase in memory and experienced less mental and physical fatigue. Persons suffering from kidney diseases will naturally have less carnitine in their bodies as the kidney is the main productive organ of this nutrient. They will thus find it beneficial to take the drug.
The side effects of the drug form are not extensive. Any person experiencing lower to borderline thyroid levels should not take it at all. People with recorded problems such as liver disease, diabetes, peripheral vascular disease, high blood pressure and history of seizures should first consult a medical professional before taking it. People have also complained about body odor while taking high doses.
A number of people have now moved on to taking a dietary supplement with this as an active ingredient as it assists with fat burning within the body. It also shows positive effects such as increasing energy levels, promoting a healthier heart and liver as well as healthy blood circulation. Although there is no solid evidence to prove that it reduces appetite, people who have been taking it have noticed a decrease in cravings and that they burnt fat at much higher speeds.
The normal carnitine supplement dose in the form of a product called L Carnitine is between five hundred and one thousand milligrams taken three times per day. The particular dosage of this magnitude will depend on the activity levels of the person who is taking it. Athletes, especially those who cycle, run, row and play team sports involving fitness, will take very high doses per day to keep up their adrenalin levels during training and performances.
The side effects of this particular brand are mostly focused on too much energy. If one takes it late in the day, sleeplessness is experienced. If taken in high quantities one may experience nausea, headaches, a blocked nose, diarrhea, and vomiting. One may also experience fever and increased blood pressure. More than one case has shown that taking this dietary product may cause anorexia nervosa, which is a physiological condition where one starves due to feeling overweight all the time.
For those individuals who do not like the thought of taking drugs, the good news is that one can get a daily carnitine supplement dose in ordinary foods. A number of vegetables, grains, and meats have high concentrations of it. Red meats such as beef and lamb have the highest concentrations while mushrooms and carrots contain too.
L-carnitine tartrate is the purest form of l-carnitine available. It is an amino acid produced naturally by the body to help burn fat and increase circulation. The overall effect of its use within the body is to produce energy. It is thought to be used for muscle movement, as well as brain and heart function.
Because of the way ALCAR is used throughout the body, it is also used as a vitamin or dietary supplement. Studies have indicated that l-carnitine tartrate may be effective for treating memory and nerve pain problems for the elderly, those with alcohol dependence, and those with diabetes.
Benefits of Amino Acids
There are a surprising number of potentially helpful effects of taking supplementary l-carnitine, however, most scientists agree that the body tends to produce the proper amounts of the amino acid. There are some studies that have shown individuals to have a deficiency, but these are isolated and rare cases or are a result of medication use. In general, l-carnitine supplements should only be taken with your doctor’s approval.
Because l-carnitine is thought to help improve memory as well as improve muscle tone and burn fat, it is used widely as a dietary supplement.
The use of l-carnitine intravenously appears to produce short-term improvement immediately in blood flow to the brain with people who have poor brain circulation.
Some testing has been done with patients who have Alzheimer’s disease, but results tend to benefit those with early-onset Alzheimer’s disease, under the age of 66.
There is no daily recommended dosage, but if you are using acetyl l-carnitine for a specific medical condition, your doctor should instruct you on how much to take and how often to take it. Dosage tends to fall within 1500mg â€“ 3000mg daily, taken in more than one dose throughout the day. For men with fertility issues, the dosage is higher but depends on body weight and age.
The only contraindications for the use of l-carnitine are to do with specific diseases and conditions. If you have ever had a seizure, you should avoid using l-carnitine. For people with a history of seizures, the use of L-carnitine has produced an increase in the seriousness and number of seizures, whether taken intravenously or orally.
Additionally, if you have an under-active thyroid gland or hypothyroidism, l-carnitine tartrate may interact with the hormones produced by the thyroid and could have a negative effect. If you know you have hypothyroidism, it is best to avoid taking additionally l-carnitine tartrate as a supplement.
Lastly, if you are pregnant or breastfeeding it is best to avoid taking l-carnitine tartrate. While no studies have shown it to have positive or negative effects, there is just not enough known about the reaction of babies to additional l-carnitine. To be on the safe side, pregnant women and breastfeeding mothers are advised not to take the supplement.
Side Effects Reported
Overall, there are very few side effects of l-carnitine. Most adults can take it safely but should check with their doctor to ensure they do not have a condition that would indicate a negative reaction. New studies and tests are conducted all the time, and it is possible that your doctor will know more about amino acid interactions than you do.
The only reported side effects, which are relatively rare and occur only in some patients, are upset stomach, restlessness, nausea, and vomiting, as well as urine, body odor, and breath that smells somewhat fishy. Because of the increase of blood flow to the brain, it may also cause you to have trouble falling asleep if taken to late in the afternoon.
The use of carnitine liquid is primarily promoted by weight loss and bodybuilding companies and websites. Carnitine is produced by the liver naturally and is an amino acid which creates energy for the body. It is thought to be essential for brain function, especially memory retention.
Carnitine also helps muscular movement, including helping the heart function properly. Because carnitine uses fat to create energy, it is touted as a weight loss miracle supplement, although conclusive studies have yet to prove this claim. Of course, when combined with regular exercise and a healthy diet, it probably does have a beneficial effect on the body.
Carnitine in its various states is used for a wide variety of medical problems, as some studies have shown it can have a positive effect on certain populations. If you suffer from memory problems related to alcohol abuse, carnitine is thought to help improve memory retention again. Alzheimer’s patients are sometimes thought to benefit from carnitine, especially in patients with early onset Alzheimer’s. If the patient is under the age of 66 and the Alzheimer’s is progressing rapidly, the use of carnitine may help delay the effects of the disease.
Patients with muscular or nerve pain due to multiple sclerosis (MS) or diabetes find some reduction of pain when they take carnitine or carnitine derivatives, such as acetyl l-carnitine (ALCAR). If you or someone you know suffers from pain from either disease, consider talking to your doctor about using liquid carnitine as a supplement.
Carnitine liquid is one of the forms that amino acid supplements can be taken. They can also be taken orally or intravenously. Liquid amino acids are easily absorbed by the body and can be easier to administer. For people with carnitine deficiencies, taking carnitine in liquid form can be enough to treat the deficiency, both in adults and in children.
There are a number of claims about the effectiveness of carnitine, especially as a liquid, but there are also a few important contraindications. If you are pregnant or breastfeeding, it is best to avoid taking carnitine in any form, as the effects on a baby are unknown. If you have ever had a seizure, you should avoid taking any carnitine supplements, as the use of l-carnitine has increased the frequency and severity of seizures for those who already experience them. And finally, if you have hypothyroidism, or a thyroid gland that is not sufficiently active, taking carnitine may have a negative effect.
While there are very few negative effects of carnitine, it is better to be safe than sorry. If you are considering using carnitine liquid to increase your metabolism, help with weight loss, or for memory or pain issues, talk to your doctor about the risks and side effects. The only reported side effects among most adults are minor and infrequent. Vomiting, nausea, upset stomach, and restlessness are the most common side effects. Additionally, you may notice that your urine, breath, and body odor smells a bit like fish.
You can also increase the levels of carnitine in your body by eating some fish, poultry, red meats, and dairy products. However, if you suffer from medical problems that prohibit you from eating any of those items, you are better off following doctors instructions about what is safe for you to eat.
The most effective way to increase the levels of carnitine in your body is to take it orally as a liquid or a tablet. However, your body does produce the amino acids you need naturally, and there may be little to no benefit to taking additional carnitine unless you have a deficiency or a serious condition which may be helped by carnitine.
Carnitine 500mg Dosage
L-Carnitine is the most popular form of the amino acid available to consumers. If you are considering taking carnitine, it is a good idea to educate yourself about the real effects, both positive and negative, as well as any risks associated with taking supplementary carnitine.
Most people can take carnitine safely, however, there are some diseases and conditions which interact negatively with increased levels of carnitine.
Dosage for Adults
Whether you are considering taking carnitine because you want to improve your memory or youâ€™ve heard that it can help you to lose weight, the dosage will be similar. Most adults can safely take 1000mg with breakfast every day, and many people who take the supplement increase that to 2000mg, 1000mg with breakfast and 1000mg with lunch. For male infertility, the recommended dosage is much higher, 2 to 3 grams per day. Studies have shown this dosage to be safe and only cause minor side effects.
Side Effects and Contraindications
Reported side effects are few and infrequent. Some adults experience nausea, vomiting, and stomach upset when taking carnitine. Additionally, due to the increased blood flow to the brain, you may find yourself a bit restless and less likely to fall asleep easily. Taking carnitine after 4 pm is not recommended, especially if you have trouble sleeping anyway.
Do not use carnitine supplements if you are pregnant or breastfeeding, if you have ever suffered from a seizure, or if you have hypothyroidism. Carnitine has been shown to increase the frequency and intensity of seizures in people who experience seizures already. It also decreases thyroid hormone activity, which can be helpful for people with hyperthyroidism but can have negative effects on people with hypothyroidism. The effects of carnitine on unborn babies or babies who are breastfeeding are unknown, so women are advised to avoid taking the supplement unless directed to by their doctor.
Carnitine Dosage and Type
Carnitine can be purchased as either a tablet or a liquid. If being administered by a doctor, it can be taken intravenously, however, most people take it in tablet or liquid form. Tablets are most common and are usually 500mg of carnitine each. For small adults, this may be a sufficient dose, depending on the reason for use. For children with carnitine deficiencies, the best way to administer carnitine is with a liquid which can be mixed with juice or water. Only give your child carnitine if directed to by a doctor and in the dosage that your doctor prescribes.
Popular Carnitine Uses
The most popular use for carnitine supplements is to aid in weight loss and muscle gain. Because carnitine is used by the mitochondria to turn fat into energy, taking carnitine regularly, in combination with an exercise regimen and a healthy diet, can help to increase the efficiency of your weight training. You may also be able to lose fat more efficiently.
Other popular uses include medical uses that are considered somewhat effective in some patients. Carnitine increases circulation to the brain, which seems to have a positive effect on those suffering from memory problems. People who are under the age of 66 and are diagnosed with early onset Alzheimerâ€™s disease may slow down the effects of the disease by taking carnitine, but results from studies are still mixed and inconclusive.
Carnitine may help with a variety of conditions, from heart disease to insufficient bone density, but again, the results from studies tend to be mixed. However, because carnitine is relatively safe and poses risks only to people with other pre-existing conditions, carnitine is probably safe to use, especially when you talk to a doctor about your suitability.
Dr Chuang is passionate about Nootropic medicine and research, bringing many years of experience to provide the most up to date and accurate information available.
Whether you are seeking a boost in concentration and focus, want to supercharge your memory and learning, or seek to improve your mood or sex life, then count on Dr Chuang for qualified, expert and authoritative comment on Nootropics.